Notes:1. For more details, such as half maximal inhibitory concentrations (IC50s) and related working concentrations of any inhibitor, please click on the link of the inhibitor of interest.
2. IC50 refers to how much of an inhibitor is needed to inhibit the activities of any kinase by 50%.
3. "+" refers to an inhibitor that has a significant effect on the specific signaling target. If the IC50 of the minor target of any inhibitor is more than 1000 times greater than the IC50 of the major target, its minor target will not be mentioned in any table.
4. There may be oversights of the effects of inhibitors on signaling targets. Please inform us if you notice any.
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